If Beoplay Portal PC PS are connected to a USB-C cable or 3.5 mm audio cable, disconnect, then reconnect the cable and try again.
If connected via Bluetooth or wireless via USB-C dongle, your Beoplay Portal PC PS have a Bluetooth range of up to 12 meters (in line of sight). However, Bluetooth connectivity might be affected by other active Bluetooth devices in the nearby area (e.g., mouse, keyboard, mobile phone, laptops, or 2.4 GHz routers). Try to keep the headphones away from other active Bluetooth devices.
Make sure to be as close as possible to your console and that the signal is not blocked.
If your Beoplay Portal PC PS are still unresponsive, find out how to reset them here.